Thus, the visceral manifestation theory was gradually established through repeated practice, synthesis and analysis. One example is that lung disease often manifests itself through a stuffed nose, and nasal discharge, which can be successfully treated from the Lung Meridian. Eventually ancient medical practitioners concluded that the lung has a connection with the nose.

As a final example, many herbs for reinforcing the kidney can also accelerate the healing of bone fractures. This derived the saying that "The kidney dominates the bone", and it was further de-duced that the kidney has a physiological role in promoting the growth and development of bones.

It is necessary to further explain that TCM pays a great deal more attention to the observation of living bodies from the philosophy of holism. It also holds that anatomy can not completely reflect functional changes of the living body, for it is only through the study of dead viscera and tissues that anatomical science is formed. Therefore, the forma-tion of the visceral manifestation theory is established on the premises of the three aspects stated above, but "physiological changes" and "pathological phenomena" can better reflect the essence of the viscera and provide the basis of the theory.