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Among other things, it stimulates the production of adrenaline, one of the hormones secreted by the adrenal glands to help us in extreme emergency situations. Our adrenals evolved to give our early ancestors the extra strength and alertness needed to escape a saber tooth tiger attack, but we don't often need that much adrenaline these days.
Like sugar, coffee constantly stimulates the production of adrenaline, putting excessive wear and tear on the adrenal glands. And let's not forget that green tea and black tea contain caffeine, and even decaf still contains some caffeine. If you're sensitive to caffeine it can keep you awake at night even if you haven't had any since noon. If you're suffering from insomnia, your best bet is to drink nonstimulating herbal teas such as chamomile or mint in the evening. If you need a boost in the afternoon, try a cup of ginseng tea.
Caffeine can have a detrimental effect on blood sugar. When caffeine is ingested, the nervous system is stimulated. Adrenaline is released and, in turn, the liver begins to emit stored blood sugar. Insulin is then released, and blood sugar drops below normal -- a common seizure trigger for people with epilepsy. Caffeine can also constrict blood vessels in the brain. It is important for people with epilepsy to know that caffeine can be an ingredient in medications, including some antihistamines and decongestants.
