Idiopathic autoimmune hemolytic anemia is an acquired disease that occurs when antibodies form against a person's own red blood cells. In the idiopathic form of this disease, the cause is unknown.
There are other types of immune hemolytic anemias where the cause may result from an underlying disease or medication. Idiopathic autoimmune hemolytic anemia accounts for one-half of all immune hemolytic anemias. The onset of the disease may be quite rapid and very serious.
Fatigue ,Pale color, Shortness of breath, Rapid heartbeat ,Yellow skin color, Dark urine ,Enlarged spleen .
The first therapy tried is usually treatment with prednisone. If prednisone does not improve the condition, a splenectomy (removal of the spleen) may be considered.
Immunosuppressive therapy is given if the person does not respond to prednisone and splenectomy. Imuran and Cytoxan have both been used.
Blood transfusions are given with caution, if indicated for severe anemia, because of the potential that blood may not be compatible and may bring on a reaction.
